





Price: $65.45
(as of Nov 14, 2025 20:39:17 UTC – Details)
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What makes our products unique?
We protect vital, bioavailable nutrients and control quality at every stage to deliver high-quality, safe products that work the way nature intended.
Why should I choose Standard Process?
We are a third generation, family-owned company with our own certified organic farm where we grow many of the ingredients found in our supplement, which are backed by science and research.
How did we get our start?
Since 1929, we have been dedicated to our whole food philosophy, providing nutrients in a whole food state where their natural potency and efficacy can be realized.
Is Discontinued By Manufacturer : No
Package Dimensions : 4.75 x 2.6 x 2.52 inches; 6.4 ounces
Item model number : 8480
Date First Available : June 12, 2018
Manufacturer : Standard Process
ASIN : B07DP646ZD
Best Sellers Rank: #7,668 in Health & Household (See Top 100 in Health & Household) #81 in Multi-Enzyme Nutritional Supplements
Customer Reviews: 4.7 4.7 out of 5 stars 3,114 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Digestion Supplement with Pancreatin: Each serving includes pancreatin, pepsin, and betaine hydrochloride to support healthy digestion; offers enzymatic support for protein digestion
Digestive Enzyme Supplement: These Zypan tablets support macronutrient digestion while stearic acid coats the pancreatin to support the digestive environment of the GI tract
Supplement Dosage: Take two HCI support supplement tablets with each meal, or as directed, and do not chew; this digestion supplement aids against acid reflex
Clean Label Supplement: This digestion supplement is gluten-free, non-grain, non-dairy, and non-soy
Standard Process: High-quality products that work the way nature intended
8 reviews for Standard Process Inc. Zypan – Digestive Health Support Supplement – HCI Supplement with Pancreatin, Betaine Hydrochloride & Pepsin – Support Macronutrient Digestion – 330 Tablets
Add a review
$65.45

George Hardt –
Helps my digestion and helps me manage Gerd.
I have Gerd. Taking this product has changed my life. I can eat most foods now with no stomach upset, which is a true blessing!
MICHAEL WINTON –
Good stuff
It’s the best stuff I have ever took 😊keeps me from bloating and feeling that terrible after eating blah
Ghost2401 –
Effective Digestive Support for Improved Nutrient Absorption
The Standard Process Zypan digestive health supplement combines betaine hydrochloride, pancreatin, and pepsin to support the breakdown and absorption of macronutrients. Designed to promote optimal digestion, this supplement is particularly useful for individuals with digestive concerns or low stomach acid. Tested over several weeks, Zypan proved to be a reliable aid for digestive health.Pros:✅ Comprehensive Formula: Contains betaine HCl for stomach acid support, pancreatin for enzyme supplementation, and pepsin for protein digestion.✅ Improved Digestion: Helps alleviate bloating, indigestion, and discomfort after meals by enhancing nutrient breakdown.✅ Trusted Brand: Produced by Standard Process, known for high-quality, science-backed supplements.✅ Convenient Dosage: Small tablets are easy to swallow, with a recommended dose of 1-2 tablets per meal.✅ Supports Macronutrient Absorption: Beneficial for individuals with impaired digestion due to low stomach acid or enzyme deficiency.Cons:❌ Potential for Over-Acidity: Individuals with normal stomach acid levels may experience discomfort; consult a healthcare provider before use.❌ Price Point: Slightly more expensive than comparable digestive enzyme supplements.Performance and Usability:Zypan delivered noticeable improvements in digestion, particularly after protein-heavy or large meals. Users reported reduced bloating and a more comfortable post-meal experience. The combination of HCl and enzymes addressed both acid and enzyme deficiencies, making it highly effective for individuals with digestion issues. However, users without a diagnosed need for HCl supplementation should approach with caution to avoid excessive acidity.Comparison:Compared to other digestive enzyme supplements, Zypan stands out for its inclusion of betaine HCl, targeting low stomach acid in addition to enzyme support. While some alternatives may focus solely on enzymes, Zypan provides a more comprehensive approach. However, it is slightly costlier than simpler formulations.Who Is This For?:Zypan is ideal for individuals with diagnosed low stomach acid, enzyme deficiencies, or digestive challenges related to protein-heavy diets. It’s particularly beneficial for those seeking targeted support for macronutrient digestion and nutrient absorption.Conclusion:The Standard Process Zypan is a reliable and effective digestive health supplement, offering a well-rounded formula for enhanced nutrient absorption and digestion. While it’s not suitable for everyone, its benefits for those with specific digestive needs make it a worthwhile investment.
AC –
I’ve been searching for years for this.
I’ve been struggling with bad digestive issues for several years. I’ve tried tons of other products, some more expensive, some less, but I’ve tried all the “best” offerings on the market as far as digestive support supplements. Well, let me say that this is the peak of the mountain as far as these supplements go. I went from slow, painful digestion to having almost no issues at all. I’ve had such an unbelievable experience with this product that I’m replacing all of my current supplements with Standard Process supplements. This is a high quality supplement from a high quality company.
nancy of Moline –
would recommend for anyone with digestive issues & with no glallbladder
great quality. Helps great when you have your gallbladder removed
Golden gal –
Ultra digestion aid
I was introduced to this product years ago and all I can say is that it works-digest your foodno bloating no burping.I use the restroom and have regular movements. It’s gold.
Iris Drake –
Reduced acid reflux
It definitely works but you need to be sure and take the dosage as recommended by the manufacturer.
balesdog –
Works
Works like a charm